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Press

May 13, 2025

Ophthalmology Times: New Research Raises Questions About the Current Clinical Approach to Inherited Retinal Diseases

By: Hattie Hayes, Martin David Harp, Alfredo Sadun, MD, PhD

Alfredo Sadun, MD, PhD, details a fascinating outcome from a gene therapy in development for Leber hereditary optic neuropathy.

During the recent Association for Research in Vision and Ophthalmology (ARVO) meeting, Alfredo Sadun, MD, PhD, chief of Ophthalmology at the Doheny Eye Institute, University of California Los Angeles, shared some exciting new research with the Eye Care Network.

In Salt Lake City, Utah, Prof. Sadun detailed a recent project examining Leber hereditary optic neuropathy (LHON). The research produced an unexpected result, but the research findings could open new possibilities for adeno-associated virus (AAV) delivery of gene therapies, especially for inherited retinal diseases.

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