- This event has passed.
LHON Forum 2023
July 23, 2023 @ 10:00 am - 1:00 pm
Event Details:
“Leber hereditary optic neuropathy (LHON) is a blinding mitochondrial disease that disproportionately affects young men. The diagnosis can be challenging with significant delays before a confirmed molecular diagnosis is reached. In this LHON Forum, we will discuss exciting developments in the field highlighting how a deeper understanding of the pathological mechanisms contributing to retinal ganglion cell loss is shaping the therapeutic landscape for this inherited optic nerve disorder.”
Program
19.00 – 19.10 LHON DISEASE DESCRIPTION (Patrick Yu-Wai-Man)
• Introduction and background
• Epidemiology
• Disease demographics
19.10 – 19.20 Proposed pathophysiology (Alfredo A. Sadun)
• Mitochondrial gene defects
• Anatomical and metabolic consideration
19.20 – 19.30 LHON CLINICAL MANIFESTATIONS (Rustum Karanjia)
19.30 – 19.40 DIAGNOSIS (Nancy J. Newman)
• Differential Diagnosis
• Clinical and Genetic diagnosis
LHON Management and Therapies
19.40 – 19.50 Visual prognosis and recovery (Nancy J. Newman)
19.50 – 20.00 Therapy/Management (Alfredo A. Sadun)
20.00 – 20.10 Follow up (Rustum Karanjia)
20.10 – 20.30 Take home messages and panel discussion with cases and Q&A