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May 26, 2025

Ophthalmology Times: ARVO 2025: OPA1 Mutation’s Effect on Retinal Ganglion Cells’ Electrical Function

By: Steven Barnes, PhD, Martin David Harp, Hattie Hayes

At ARVO 2025, in Salt Lake City, Utah, Steven Barnes, PhD, talked about his research on the OPA1 mutation in retinal ganglion cells’ effect on the cell’s electrical function.

The below transcript has been lightly edited for clarity.

Steven Barnes, PhD:
Hi, I’m Steve Barnes. I have a PhD in retinal neurobiology, and I’m a professor at UCLA, working at the Doheny Eye Institute. I’ve been to about 20 ARVO meetings over the decades, and it’s always been great, and it’s always exciting to bring your latest discoveries in research to the meeting. The project we’re presenting at ARVO is about human stem cell-derived retinal ganglion cells, the cells that die in diseases such as glaucoma and many other optic neuropathies.

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