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Barnes Lab Group

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Publications

Partial list including past 6 years, plus early highlights

  • Barnes S (2022). Visual processing: When two synaptic strata are better than one. Current Biology (In press).
  • Zhang X, Mandric I, Nguyen KH, Nguyen TTT, Pellegrini M, Grove JCR, Barnes S and Yang X-J (2021). Single Cell Transcriptomic Analyses Reveal the Impact of bHLH Factors on Human Retinal Organoid Development. Frontiers in Cell Developmental Biology 9:653305. doi: 10.3389/fcell.2021.653305. PMCID: PMC8155690
  • Hirano AA, Vuong HE, Kornmann HL, Schietroma C, Stella SL Jr, Barnes S, Brecha NC (2020). Vesicular release of GABA by mammalian horizontal cells mediates inhibitory output to photoreceptors. Frontiers in Cellular Neuroscience 14:600777. doi: 10.3389/fncel.2020.600777
  • Barnes S, Grove JCR, McHugh CF, Hirano AA, Brecha NC (2020). Horizontal cell feedback to cone photoreceptors in mammalian retina: Novel insights from the GABA-pH hybrid model. Frontiers in Cellular Neuroscience 14:595064. doi: 10.3389/fncel.2020.595064.
  • Grove JCR, Hirano AA, de los Santos J, McHugh CF, Purohit S, Field GD, Brecha NC, Barnes S (2019). Novel hybrid action of GABA mediates inhibitory feedback in the mammalian retina. PLOS Biology 13(12):e1002322. doi:10.1371/journal.pbio.1002322. PMCID: PMC6459543.
  • Hirano A, Liu X, Brecha N, Barnes S (2018). Analysis of feedback signaling from horizontal cells to photoreceptors in mice. In Mouse Retinal Phenotyping -Methods and Protocols, Methods in Molecular Biology (Tanimoto N, Ed) Springer. Vol. 1753. doi: 10.1007/978-1-4939-7720-8_12.
  • Sun XP, Liu X, Hirano AA, Brecha NC, Barnes S. (2017) Calcium-activated BK channels govern dynamic membrane potentials of horizontal cells in rodent retina. Journal of Physiology 595:4449-4465. doi: 10.1113/JP274132. PMCID: PMC5491872.
  • Hirano AA, Barnes S, Brecha NC (2017) Retina: Information Processing: Horizontal Cells. In Reference Module in Neuroscience and Biobehavioral Psychology, Elsevier. ISBN 9780128093245
  • Liu X, Grove JC, Hirano AA, Brecha NC, Barnes S. (2016) Dopamine modulation of calcium channel currents in horizontal cells of mouse retina. Journal of Neurophysiology 116:686-697. PMCID: PMC4982899.
  • Matynia A, Nguyen E, Sun XP, Blixt FW, Parikh S, Kessler J, Pérez de Sevilla Müller L, Habib S, Kim P, Wang ZZ, Rodriguez A, Charles A, Nusinowitz S, Edvinsson L, Barnes S, Brecha NC, Gorin MB (2016) Peripheral sensory neurons expressing melanopsin respond to light. Front. Neural Circuits 10:60. doi: 10.3389/fncir.2016.00060 PMCID: PMC4978714.
  • Hirano AA, Liu, X, Boulter J, Grove J, Pérez de Sevilla Müller L, Barnes S, Brecha NC. (2016) Targeted deletion of vesicular GABA transporter from retinal horizontal cells eliminates feedback modulation of photoreceptor calcium signaling. eNeuro 3(2) e0148-15.2016 1–13. PMCID: PMC4785380.
  • Vuong HE, Hardi CN, Barnes S, Brecha NC (2015) Parallel inhibition of dopamine amacrine cells and intrinsically photosensitive retinal ganglion cells in a non-image-forming visual circuit of the mouse retina. Journal of Neuroscience 35:15955-15970. PMCID: PMC4666919.
  • Farrell SR, Rankin DR, Brecha NC, Barnes S (2014) Somatostatin receptor subtype 4 modulates L-type calcium channels via G and PKC signaling in rat retinal ganglion cells. Channels 8:519-527. Erratum in: Channels (Austin) 2015; 9:56-57. PMCID: PMC4594562.
  • Sargoy A, Barnes S, Brecha N, Perez de Sevilla Muller L (2014) Immunohistochemical and calcium imaging methods in whole-mount rat retina. Journal of Visualized Experiments 92:e51396. PMCID: PMC4621789.
  • Farrell S, Sargoy A, Brecha N, Barnes S (2014) Modulation of voltage-gated Ca channels in rat retinal ganglion cells by gabapentin. Visual Neuroscience 31:47-55. PMCID: PMC4618165.
  • Sargoy A, Sun XP, Barnes S, Brecha N (2014) Differential calcium signaling mediated by voltage-gated calcium channels in rat retinal ganglion cells and their unmyelinated axons. PLoS ONE 9:e84507. PMID: 24416240 PMCID: PMC3885580
  • Liu X, Hirano A, Sun XP, Brecha N, Barnes S (2013) Calcium channels in rat horizontal cells regulate feedback inhibition of photoreceptors through an unconventional GABA- and pH-sensitive mechanism. Journal of Physiology 591:3309-3324. PMCID: PMC3717229.
  • Trenholm S, Borowska J, Zhang JC, Hoggarth A, Johnson K, Barnes S, Lewis T, Awatramani G (2012) Intrinsic oscillatory activity arising in the electrically-coupled AII amacrine/On cone bipolar cell network of degenerated retina is driven by Na channels. Journal of Physiology 590:2501-2517. PMID: 22393249 PMCID: PMC3424767
  • Vessey JP, Stratis AK, Daniels BA, Da Silva N, Jonz MG, Lalonde MR, Baldridge WH, Barnes S (2005) Proton-mediated feedback inhibition of presynaptic calcium channels at the cone photoreceptor synapse. Journal of Neuroscience 25:4108-4117. PMCID: PMC15843613
  • Mansergh F, Orton NC, Vessey JP, Lalonde MR, Stell WK, Tremblay F, Barnes S, Rancourt DE, Bech-Hansen NT (2005) Mutation of the Ca channel gene Cacna1f disrupts calcium signaling, synaptic transmission and cellular organization in mouse retina. Human Molecular Genetics 14:3035-3046. PMCID: PMC16155113
  • Savchenko A, Barnes S, Kramer RH (1997) Cyclic nucleotide-gated channels in synaptic terminals mediate feedback modulation by nitric oxide. Nature 390:694-698. PMCID: PMC9414163
  • Piccolino M, Byzov AL, Kurenny DE, Pignatelli A, Sappia F, Wilkinson MF, Barnes S (1996) Low-calcium-induced enhancement of chemical synaptic transmission from photoreceptors to horizontal cells in the vertebrate retina. Proceedings of the National Academy of Science (U.S.A.) 93:2302-2306. PMCID: PMC8637867
  • Kurenny DE, Moroz LL, Turner RW, Sharkey KA , Barnes S (1994) Modulation of ion channels in rod photoreceptors by nitric oxide. Neuron 13:315-324. PMCID: PMC7520253
  • Barnes S, Merchant V, Mahmud F (1993) Modulation of transmission gain by protons at the photoreceptor output synapse. Proceedings of the National Academy of Science (U.S.A.) 90:10081-10085. PMCID: PMC7694280
  • Barnes S, Bui Q (1991) Modulation of calcium-activated chloride current via pH-induced changes of Ca channel properties in cone photoreceptors. Journal of Neuroscience 11:4015-4023. PMCID: PMC1660538
  • Barnes S, Hille B (1989) Ionic channels of the inner segment of tiger salamander cone photoreceptors. Journal of General Physiology 94:719-743. PMCID: PMC2482325
  • Beech DJ, Barnes S (1989) Characterization of voltage-gated K channels that accelerate the rod response to dim light. Neuron 3:573-581. PMCID: PMC2642011
  • Barnes S, Werblin F (1986) Gated currents generate single spike activity in amacrine cells of tiger salamander retina. Proceedings of the National Academy of Science (U.S.A.) 83:1509-1512. PMCID: PMC3456599